Comprehensive CDMO Services for Pharma, Food, IVD, and Cosmetics

The Inteelabs team possesses a wealth of diverse experience in successfully developing challenging-to-express and purify proteins using various expression systems.

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Our expertise spans from formulating strategic plans to establishing characterized cell banks, and executing each milestone with precision, ensuring well-defined outcomes. With our extensive background in cultivating high-expression strains through carefully selected vector combinations, we tailor our strategies to align with the specific application of the protein.

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Inteelabs offers a comprehensive range of services, catering to both microbial and mammalian hosts.

Expression and purification screening play a crucial role in establishing the optimal expression system and process conditions by evaluating various expression host systems. This process is essential for developing a cost-effective approach suitable for scale-up studies.

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Our scouting matrix encompasses a range of expression and purification parameters. To address the unique properties of the protein, we have tailored procedures for extraction, purification, and solubilization. Expression scouting is invaluable for selecting a confirmed expression system and refining the process as we move towards the development stage.

Process development involves a comprehensive range of research and development endeavors aimed at establishing a resilient, replicable, scalable, and cost-effective process by optimizing a multitude of physical and biological parameters.

Our approach to process development consistently commences with a well-defined objective, marked by specific milestones and stringent timelines that we steadfastly adhere to in our commitment to delivering superior-quality products and services.

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The key to Inteelabs' ability to deliver top-tier products and processes that align with desired growth, productivity, and purity lies in a harmonious blend of strategy, technology, and stringent controls. We employ high-throughput screening techniques for both upstream parameters and downstream unit operations, resulting in reduced timelines and lowered costs of goods.

Scale-up studies are conducted to expand the production of recombinant molecules, utilizing the well-established optimal expression conditions. Our services include process scale-up capabilities, enabling the production of recombinant molecules on a large scale to support advanced research.

Our production facility is equipped to handle microbial and mammalian cell- derived products, boasting bioreactors with capacities starting from 5L, 7L, 14L, 30L, 100L & 300L.

Analytical characterization is conducted using a range of biophysical and biological methods, aimed at comprehending the physical and biochemical attributes of molecules. This comprehensive approach encompasses a variety of sophisticated techniques, such as UV-Vis spectrophotometry, High-Performance Liquid Chromatography (HPLC), Dynamic Light Scattering (DLS), Mass Spectrometry, and Microplate Reader, among others. Notably, all of these state-of-the-art instruments are readily accessible within the facilities of BSC BioNEST Bio-Incubator (BBB). This strategic advantage empowers our company to deliver products backed by high-quality data derived from these cutting-edge analytical instruments.